In the Pollack Lab, we study interesting and relevant biophysical problems involving proteins, RNA, and DNA. With eight national research centers and laboratories focused on applied physics–four of which are supported by the National Science Foundation–our graduate students have access to some of the most advanced research equipment and technology in the world.
Nucleic acids are among the most highly charged polymers found in nature, yet their biological roles require them to fold or condense into tightly packaged structures. We are studying the role of positively charged ions on these dramatic conformational changes.
Proteins carry out many important tasks related to life. We are interested in proteins as sensors of signals, such as light or ligands. We study how proteins transduce environmental signals into cellular information.